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Due to their particular susceptibility to WNV infection, horses serve as a sentinel species. In this book, specialists in 11 emerging zoonotic viruses present detailed information on each virus's structure, molecular biology, current geographic distribution, and method of transmission. disease in horses. It is most commonly spread to people by the bite of an infected mosquito. West Nile virus (WNV) testing is used to help determine whether a person with signs and symptoms and a history of recent exposure has an acute WNV infection. Currently, no drugs cure West Nile virus infection or vaccines for humans to prevent the disease, which emerged across the country in 1999 and is now found in every state except Alaska and Hawaii. Infection can lead to a series of severe symptoms, most commonly encephalitis - acute inflammation of the brain. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. Severe neurological symptoms develop in ~8% of exposed horses, and once symptoms manifest, the fatality rate ranges from 20-40% . The aim of this book was to assemble an up-to-date and cutti- edge anthology from the leading experts in the field. Genetics; Gerontology & Geriatrics . If you have problems viewing PDF files, download the latest version of Adobe Reader, For language access assistance, contact the NCATS Public Information Officer, Genetic and Rare Diseases Information Center (GARD) - PO Box 8126, Gaithersburg, MD 20898-8126 - Toll-free: 1-888-205-2311. We remove all identifying information when posting a question to protect your privacy. To understand the genetic makeup of the Culex mosquito, and how the insect is able to transmit this and other viruses, scientists have . These resources provide more information about this condition or associated symptoms. Originally isolated from a febrile patient in Uganda in 1937 (Ref. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies. In about 80% of infections people have few or no symptoms. RNA viral replication is highly . This essential, authoritative handbook provides clear, accurate coverage of zoonoses — diseases that can spread from animals to humans. It was first iso-lated in the West Nile province of Uganda from a woman with fever. Research helps us better understand diseases and can lead to advances in diagnosis and treatment. These resources provide more information about this condition or associated symptoms. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, ... “Understanding the genetic determinants that affect West Nile virus susceptibility and resistance is of utmost importance,” he says. We are currently developing a new version of GARD. West Nile virus (WNV) is the leading cause of mosquito-borne disease in the continental United States. West Nile virus (WNV) is a mosquito-borne zoonotic neurotropic virus capable to cause lethal meningoencephalitis (WNE) in infected hosts such as birds, horses, and humans.

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