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Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Acute Liver Failure 5. How long before a meal should you take ondansetron? Last updated on Nov 11, 2020. Ondansetron is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy.It is also used to prevent or treat nausea and vomiting after surgery. Ondansetron orally disintegrating tablet may cause drowsiness. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. Medically reviewed by Drugs.com. Hundreds of women have turned to the legal system to get justice and restitution for unexpected side effects that have changed lives forever. It is also used to prevent or treat nausea and vomiting after surgery. Some of the dosage forms listed on this page may not apply to the brand name Zofran. Side effects. In the ondansetron prescribing label information (Zofran®, Zofran ODT® package insert), the most commonly reported ondansetron (Zofran®, Zofran ODT®) side effects are shown here. [Ref], Common (1% to 10%): Injection site reactions[Ref], Rare (0.01% to 0.1%): Immediate hypersensitivity reactions (sometimes severe), anaphylaxis/anaphylactoid reactions, Frequency not reported: Poor oral intake[Ref], 1. Most patients were receiving concomitant chemotherapy with cisplatin. Abnormally Low Blood Pressure 4. What Is Ondansetron? Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. Ondansetron is a common medication that can be used to treat vomiting in dogs and cats. Seek immediate care if you experience an irregular heartbeat, shortness of breath, dizziness, or fainting while taking Zofran (ondansetron). Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Strativa Pharmaceuticals, a Division of Par Pharmaceuticals, Inc., Woodcliff Lake, NJ. [Ref], Very common (10% or more): Eye disorder (up to 19%), Common (1% to 10%): Visual disturbance/transient visual disturbances (e.g., blurred vision), Very rare (less than 0.01%): Transient blindness, Frequency not reported: Swollen periocular area[Ref], Cardiopulmonary arrest and shock occurred during allergic reactions in patients given the IV formulation. [Ref], Very common (10% or more): Headache (up to 27%), drowsiness/sedation (up to 23%), Common (1% to 10%): Dizziness, paresthesia, Uncommon (0.1% to 1%): Seizures, movement disorders/extrapyramidal reactions (oculogyric crisis/dystonic reactions, dyskinesia), Rare (0.01% to 0.1%): Grand mal seizures[Ref]. Some side effects may not be reported. Zofran side effects Get emergency medical help if you have any of these signs of an allergic reaction to Zofran: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Headache occurred more often in the oral dissolving tablet formulation when taken with water. The most concerning side effects of Zofran include effects on the heart rhythm, a potential for birth defects and a condition known as serotonin syndrome. What Are Side Effects of Zofran? Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If experienced severely or for a … Read this article to learn more about dosage and side effects. Zofran® May Cause Harmful Interactions With Certain Foods, Drugs, And Medical Conditions There's a lot of controversy surrounding the anti-nausea medication Zofran®, particularly when it's used by pregnant women. Slow Heartbeat 14. Along with its needed effects, ondansetron (the active ingredient contained in Zofran) may cause some unwanted effects. At the extreme end, the use of the drug caused fetal death including miscarriage and stillbirth. In fact, along with the risks of birth defects in their infants, other side effects that directly affect the mother include: These side effects may go away during treatment as your body adjusts to the medicine. Doctors also prescribe it to pregnant women who have extreme or debilitating morning sickness. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. Dizziness occurred during rapid IV administration. 3. Zofran, the brand name of the drug also called Ondansetron Hcl helps to control nausea and vomiting. Abnormal Heart Electrical Signals 2. If these effects persist or worsen, notify your doctor promptly. Bronchospasm 6. WebMD does not provide medical advice, diagnosis or treatment. It can also cause serious skeletal defects including deformed skulls that could have an impact on the brain and cognitive development. The safety of Zofran during pregnancy is an issue in Canada as well. The National Institutes of Health lists the following as common side effects. Fast Heartbeat 9. Applies to ondansetron: film, solution, tablet, tablet disintegratingOther dosage forms: 1. injection solutionAlong with its needed effects, ondansetron (the active ingredient contained in Zofran) may cause some unwanted effects. O 0. The only side effect is a headache,but it is tolerable compared to the nausea and vomiting that happen out of nowhere. If these effects persist or worsen, notify your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the … Note: This document contains side effect information about ondansetron. Zofran Side Effects Include Injuries to Mothers and Babies. If experienced, these tend to have a Severe expression 1. Ondansetron (Zofran) is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Prolonged QT Interval On EKG 12. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. 4. It is unknown if Zofran enters breast milk. More common side effects. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking onda… Shock 13. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. It is ineffective for treating vomiting caused by motion sickness. Zofran side effects Get emergency medical help if you have signs of an allergic reaction to Zofran: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Although not all of these side effects may occur, if they do occur they may need medical attention. Oculogyric crisis occurred alone and in combination with other dystonic reactions. Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. Stevens-Johnson Syndrome 15. This drug is more popular than comparable drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Cerner Multum, Inc. "UK Summary of Product Characteristics." Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. The following article provides more detailed information on the use, side effects, and drawbacks of this drug. There are some side effects associated with Zofran. Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. Common Zofran side effects include: Zofran (ondansetron)." The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Check with your doctor immediately if any of the following side effects occur while taking ondansetron: Some side effects of ondansetron may occur that usually do not need medical attention. It is available in both brand and generic form. All medications have side effects, including Zofran. Most side effects of Zofran are mild or moderate, but some may be severe or life-threatening. If you struggle with nausea … This drug is more popular than comparable drugs. Zofran is a drug with problematic side effects. Zofran Complaints Reported in Canada. Cerner Multum, Inc. "Australian Product Information." Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Temporary Blindness 16. Many of the cases of blindness resolved from within a few minutes to approximately 28 hours. Zofran (ondansetron) is fast-acting and starts working within 30 minutes. [Ref], Common (1% to 10%): Anxiety/agitation, disturbance in behavior/conduct, sleep disturbance[Ref], Common (1% to 10%): Gynecological disorder, urinary retention, urinary tract infection/dysuria[Ref], Very rare (less than 0.01%): Toxic skin eruption, toxic epidermal necrolysis[Ref], Common (1% to 10%): Asymptomatic increases in AST/ALT, Postmarketing reports: Liver failure and death[Ref]. Many pregnant women have relied on anti-nausea medications to get them through the first few months of pregnancy, when nausea is at its peak. side effects The following have been reported as adverse events in clinical trials of patients treated with ondansetron, the active ingredient of ondansetron hydrochloride tablets. Side Effects. Zofran is available in generic form. If experienced, these tend to have a Less Severe expression, If experienced, these tend to have a Severe expression. Side Effects. Abnormal Liver Function Tests 3. O 0. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to ondansetron: injectable solution, intravenous solution, oral disintegrating strip, oral solution, oral tablet, oral tablet disintegrating, The most frequently reported side effects are headache, constipation, and diarrhea. 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