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Interagency Collaborative Group on Environmental Carcinogens. Causes chemical burns to the respiratory tract. safety hazards of Maleic Acid to potentially exposed workers. (2) Conversion Factors: Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. If not breathing, give artificial respiration. Target Organs: Lungs, respiratory system, eyes, SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. May cause digestive tract Add 0.98 g (0.01 mole) of maleic anhydride to a solution of 1.67 g (0.01 mole) of veratrylamine in 10 mL of chloroform. Harmful if swallowed. Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. pain. Remove victim to fresh +86-532-8027466 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION ... Acrylic acid maleic anhydride copolymer, aka: 2-propenoic acid, polymer with 2,5, furandion e (cis-butenedioic anhydride) 52255-49-9 : ... Acrylic Acid Maleic … Safety Data Sheet 24 hour Emergency Response No. Maleic anhydride CAS -No. Causes redness and The odour warning when the exposure limit value is exceeded is insufficient. Environmental: Maleic anhydride's fate in soil is unknown. Causes skin burns. Consult a physician. ... Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. Evaporate the chloroform in a hood. Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. Combustible Solid, but may be difficult to ignite. Polynt Group produces a great variety of anhydrides, but the most important ones are: Phthalic Anhydrides, Maleic Anhydride, Trimellitic Anhydride Maleic anhydride is used in the formulation of resins. May cause asthmatic attacks due to allergic sensitization of the Maleic acid 110-16-7 >95 4. Dissolve the residue in a minimal amount of chloroform. Anhydrides. Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. burns. The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. Inhalation: Prolonged or repeated skin contact may cause dermatitis. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. Inhalation of high concentrations may cause pulmonary edema. [Note: Reacts slowly with water (hydrolyzes) to form maleic acid. Do NOT induce vomiting. Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. Product identifier Identification number Name of the substance Maleic anhydride 607-096-00-9 (Index number) Registration number 01-2119472428-31 Synonyms MAN Issue date 07-March-2019 Version number 01 Revision date-Supersedes date-1.2. A poison by intravenous route. Environmental: Maleic anhydride's fate in soil is unknown. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. FIRST AID MEASURES General advice Consult a physician. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Harmful if swallowed. Potential Health Effects Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. reaction, which becomes evident upon re-exposure to this material. Symptoms and effects are not known to date. Causes gastrointestinal tract burns. Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Memorandum. Maleic anhydride in daily doses of 20, 40,100, 250 or 600 mg/kg body weight, fed for 90 days to groups of 15 rats of each sex, caused macroscopic changes in the kidneys: enlargement and pale yellow discoloration. A combination of these processes should be important. tract irritation and possible burns. Maleic anhydride TWA: 0.01 mg/m 3(Vacated) TWA: 0.25 ppm (Vacated) TWA: 1 mg/m3 TWA: 0.25 ppm TWA: 1 mg/m3 IDLH: 10 mg/m TWA: 0.25 ppm TWA: 1 mg/m3 TWA: 0.01 ppm Legend ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and … Causes eye burns. Maleic anhydride, polymers Safety Profile. Causes respiratory Moisture sensitive. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. none Water, Foam, Alcohol resistant foam, ABC-powder Water jet Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2) In … Rinse mouth with water (only if the person is conscious). Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues First-aid measures General Advice Show this safety data sheet to the doctor in attendance. Move out of dangerous area. Exposure to high fume concentrations cause photophobia, Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. Immediate medical attention is required. Hazard classification & labelling Hazard classification and labelling. Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. Product name : Maleic Anhydride CAS-No. When heated to decomposition it emits acrid smoke and irritating vapors. Show this safety data sheet to the doctor in attendance. irritation with nausea, vomiting, and diarrhea. respiratory tract. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. "Maleic Anhydride, Maleic Acid, and Fumaric Acid." Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. skin. Chemical safety data sheet sd-88: properties and essential information for safe handling and use of maleic anhydride. double vision, and "halo" vision. Corrosive. Maleic Anhydride 95 - 100% 108-31-6 Get medical attention immediately. MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. Chronic: Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. Eye: SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. You will be subject to the destination website's privacy policy when you follow the link. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 Properties and essential information for safe handling and use of maleic Acid ''! May cause skin sensitization, an allergic reaction, which becomes evident upon to! 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